Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $243.95 | Total: $1,219.75 |
| 1 | 10 | $206.64 | Total: $2,066.40 |
| 1 | 25 | $175.07 | Total: $4,376.75 |
| 1 | 50 | $149.24 | Total: $7,462.00 |
| 1 | 100 | $129.15 | Total: $12,915.01 |
Overview
MRTX-9768 is a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAPCDKN2A-deleted tumors.
Chemical Properties
| Molecular Formula | C24H17FN6O |
| Molecular Weight | 424.43 |
| CAS Numbers | 2629314-68-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cn1ncc(c1-c1c(F)cc2ccccc2c1C#N)-c1ccc2c(c1)c(CN)n[nH]c2=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Christopher R. Smith, et al. Abstract LB003 Fragment based discovery of MRTX9768, a synthetic lethal-based inhibitor designed to bind the PRMT5-MTA complex and selectively target MTAPCDKN2A-deleted tumors. Cancer Res 1 July 2021; 81 [13_Supplement] LB003.