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Capzimin
AOB8855
CAS No: 2084867-65-0
Chemical Name: CZM; 8-Mercapto-N-(2-(thiazol-2-yl)ethyl)quinoline-3-carboxamide
979 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.05 | Total: $225.25 |
| 1 | 10 | $38.16 | Total: $381.60 |
| 1 | 25 | $32.33 | Total: $808.25 |
| 1 | 50 | $27.56 | Total: $1,378.00 |
| 1 | 100 | $23.85 | Total: $2,385.00 |
Overview
Novel potent and specific inhibitor of proteasome isopeptidase Rpn11
Chemical Properties
| Molecular Formula | C15H13N3OS2 |
| Molecular Weight | 315.41 |
| CAS Numbers | 2084867-65-0 |
| Solubility | DMSO |
| Purity | 99% (HPLC) |
| IUPAC/Chemical Name | 8-Mercapto-N-(2-(thiazol-2-yl)ethyl)quinoline-3-carboxamide |
| InChl Key | MYNGHZGMRXNEEH-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C15H13N3OS2/c19-15(17-5-4-13-16-6-7-21-13)11-8-10-2-1-3-12(20)14(10)18-9-11/h1-3,6-9,20H,4-5H2,(H,17,19) |
| SMILES Code | O=C(C1=CC2=CC=CC(S)=C2N=C1)NCCC3=NC=CS3 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
Li J, Yakushi T, Parlati F, Mackinnon AL, Perez C, Ma Y, Carter KP, Colayco S, Magnuson G, Brown B, Nguyen K, Vasile S, Suyama E, Smith LH, Sergienko E, Pinkerton AB, Chung TDY, Palmer AE, Pass I, Hess S, Cohen SM, Deshaies RJ. Capzimin is a potent and specific inhibitor of proteasome isopeptidase Rpn11. Nat Chem Biol. 2017 May;13(5):486-493. doi: 10.1038/nchembio.2326. Epub 2017 Feb 28. PubMed PMID: 28244987.
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