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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $288.15 | Total: $1,440.75 |
| 1 | 10 | $244.08 | Total: $2,440.80 |
| 1 | 25 | $206.79 | Total: $5,169.75 |
| 1 | 50 | $176.28 | Total: $8,814.00 |
| 1 | 100 | $152.55 | Total: $15,255.01 |
Overview
INT-767 is a potent farnesoid X receptor (FXR)TGR5 dual agonist that prevents NASH and promotes visceral adipose brown lipogenesis and mitochondrial function for the study of non-alcoholic steatohepatitis.
Chemical Properties
| Molecular Formula | C25H43NaO6S |
| Molecular Weight | 494.66 |
| CAS Numbers | 1000403-03-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O[C@H]1[C@]2([H])[C@@](CC[C@]3([C@@]2([H])CC[C@]3([H])[C@H](C)CCOS(=O)([O-])=O)C)([H])[C@@]4([C@](C[C@@H](CC4)O)([H])[C@H]1CC)C.[Na+] |
Storage and Handling
0C Short Term, -20C Long Term
References
Baghdasaryan A, et al. Dual farnesoid X receptorTGR5 agonist INT-767 reduces liver injury in the Mdr2-- [Abcb4--] mousecholangiopathy model by promoting biliary HCO3- output. Hepatology. 2011 Oct;54[4] 1303-1312.