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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $71.40 | Total: $357.00 |
| 1 | 10 | $60.48 | Total: $604.80 |
| 1 | 25 | $51.24 | Total: $1,281.00 |
| 1 | 50 | $43.68 | Total: $2,184.00 |
| 1 | 100 | $37.80 | Total: $3,780.00 |
Overview
NDB is a selective and potent hFXR? antagonist that inhibits GW4064-stimulated FXRRXR interactions and FXR? target gene expression in primary mouse hepatocytes.NDB is used in the study of diabetes.
Chemical Properties
| Molecular Formula | C26H28Cl2N2O2 |
| Molecular Weight | 471.42 |
| CAS Numbers | 1660153-08-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN(C)c1cc(Cl)c(C(=O)N(Cc2ccccc2)c2ccc(O)c(c2)C(C)(C)C)c(Cl)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Xu X,et al. Structural Basis for Small Molecule NDB [N-Benzyl-N-[3-[tert-butyl]-4-hydroxyphenyl]-2,6-dichloro-4-[dimethylamino] Benzamide] as a Selective Antagonist of Farnesoid X Receptor ? [FXR?] in Stabilizing the Homodimerization of the Receptor. J Biol Chem. 2015 Aug 7;290[32] 19888-99.