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ML353 (VU0478006)
AOB2937
CAS: 2990506-75-5
Chemical Name: VU0478006; 3-Azabicyclo[3.1.0]hexan-3-yl-[5-[2-(3-fluorophenyl)ethynyl]pyridin-2-yl]methanone
2000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | 1 mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $24.65 | Total: $123.25 |
| 1 | 10 | $20.88 | Total: $208.80 |
| 1 | 25 | $17.69 | Total: $442.25 |
| 1 | 50 | $15.08 | Total: $754.00 |
| 1 | 100 | $13.05 | Total: $1,305.00 |
Overview
Novel Silent Allosteric Modulator (SAM) of the Metabotropic Glutamate Receptor 5
Chemical Properties
| Molecular Formula | C19H15FN2O |
| Molecular Weight | 306.33 |
| CAS Numbers | 2990506-75-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 3-Azabicyclo[3.1.0]hexan-3-yl-[5-[2-(3-fluorophenyl)ethynyl]pyridin-2-yl]methanone |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
ML-353; ML 353; VU0478006; VU 0478006; VU-0478006
References
1) Karen J. Gregory et al., Identification of a high affinity MPEP-site silent allosteric modulator (SAM) for the metabotropic glutamate subtype 5 receptor (mGlu5); Probe Reports from the NIH Molecular Libraries Program 2010
2) Zoltán Orgován et al. Allosteric Molecular Switches in Metabotropic Glutamate Receptors, Chemistry Europe, (2020). doi.org/10.1002/cmdc.202000444