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Clerosterol
AOB30146
CAS No :2364-23-0
Chemical Name: Poriferasta-5,25-dien-3beta-ol; 5,25-Stigmastadienol; NSC144945; (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-Ethyl-6-methylhept-6-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
452 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $126.65 | Total: $633.25 |
| 1 | 10 | $107.28 | Total: $1,072.80 |
| 1 | 25 | $90.89 | Total: $2,272.25 |
| 1 | 50 | $77.48 | Total: $3,874.00 |
| 1 | 100 | $67.05 | Total: $6,705.00 |
Overview
Natural inhibitor of Pgp activity, decreasing cisplatin uptake in BRL cells mainly through increasing Mrp2 gene expression, also decreasing the uptake of colchicine in HEK 293 cells by increasing both Pgp and Mrp1 activity
Chemical Properties
| Molecular Formula | C29H48O |
| Molecular Weight | 412.70 |
| CAS Numbers | 2364-23-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (3S,8S,9S,10R,13R,14S,17R)-17-[(2R,5S)-5-Ethyl-6-methylhept-6-en-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol |
| SMILES Code | C[C@@]12[C@](CC[C@]2([H])[C@H](C)CC[C@H](CC)C(C)=C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C |
Synonyms
NSC144945
References
1) Kim AD, et al. Cytotoxic effect of clerosterol isolated from Codium fragile on A2058 human melanoma cells. Mar Drugs. 2013 Feb 6;11(2):418-30
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