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10-Cl-BBQ
AOB2641
CAS: 23982-76-5
Chemical Name: 10-Chloro-7H-benzimidazo[2,1-a]benzo[de]Iso-quinolin-7-one
1731 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $12.75 | Total: $63.75 |
| 1 | 10 | $10.80 | Total: $108.00 |
| 1 | 25 | $9.15 | Total: $228.75 |
| 1 | 50 | $7.80 | Total: $390.00 |
| 1 | 100 | $6.75 | Total: $675.00 |
Overview
Potent aryl hydrocarbon receptor (AhR) ligand
Chemical Properties
| Molecular Formula | C18H9ClN2O |
| Molecular Weight | 304.73 |
| CAS Numbers | 23982-76-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 10-Chloro-7H-benzimidazo[2,1-a]benz[de]isoquinolin-7-one |
| InChl Key | ZJESJVGSDQOZAT-UHFFFAOYSA-N |
| SMILES Code | ClC1=CC2=C(N=C3N2C(C4=CC=CC5=C4C3=CC=C5)=O)C=C1 |
| PubChem ID | 1778614 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Punj et al (2014) Benzimidazoisoquinolines: a new class of rapidly metabolized aryl hydrocarbon receptor (AhR) ligands that induce AhR-dependent Tregs and prevent murine graft-versus-host disease. PLoS One 9 e88726 PMID: 24586378
2) Ehrlich et al (2016) Activation of the aryl hydrocarbon receptor by 10-Cl-BBQ prevents insulitis and effector T cell development independently of Foxp3+ regulatory T Cells in nonobese diabetic mice. J.Immunol. 196 264 PMID: 26573835
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