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ML145
AOB1552
CAS: 1164500-72-4
Chemical Name: 2-Hydroxy-4-[4-[(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoylamino]benzoic acid; ML-145
300 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.45 | Total: $157.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 100 | $16.65 | Total: $1,665.00 |
Overview
Selective GPR35 antagonist
Chemical Properties
| Molecular Formula | C24H22N2O5S2 |
| Molecular Weight | 482.57 |
| CAS Numbers | 1164500-72-4 |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2-Hydroxy-4-[4-(5Z)-5-[(E)-2-methyl-3-phenylprop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanoylamino]benzoic acid |
| InChl Key | COFMYJWNXSFLKQ-QIROLCGISA-N |
| SMILES Code | O=C(NC3=CC=C(C(O)=O)C(O)=C3)CCCN2C(/C(SC2=S)=C/C(C)=C/C1=CC=CC=C1)=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Heynen-Genel et al (2010) Antagonists for the orphan receptor GPR35. Probe Reports from the Molecular Libraries Program NBK5070
2) Jenkins et al (2012) Antagonists of GPR35 display high species ortholog selectivity and varying modes of action. J.Pharmacol.Exp.Ther. 343 683 PMID: 22967846