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OPC-21268
AOB6575
CAS: 131631-89-5
Chemical Name: N-[3-[4-[[4-(3,4-Dihydro-2-oxo-1(2H)quinolinyl)-1-piperidinyl]carbonyl]phenoxy]propyl]-acetamide
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $17.85 | Total: $89.25 |
| 1 | 10 | $15.12 | Total: $151.20 |
| 1 | 25 | $12.81 | Total: $320.25 |
| 1 | 50 | $10.92 | Total: $546.00 |
| 1 | 100 | $9.45 | Total: $945.00 |
Overview
Nonpeptide vasopressin V1 receptor antagonist
Chemical Properties
| Molecular Formula | C26H31N3O4 |
| Molecular Weight | 449.55 |
| CAS Numbers | 131631-89-5 |
| Solubility | DMSO and Alcohol |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | N-(3-(4-(4-(2-oxo-3,4-dihydroquinolin-1(2H)-yl)piperidine-1-carbonyl)phenoxy)propyl)acetamide |
| InChl Key | KSNUCNRMDYJBKT-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C26H31N3O4/c1-19(30)27-15-4-18-33-23-10-7-21(8-11-23)26(32)28-16-13-22(14-17-28)29-24-6-3-2-5-20(24)9-12-25(29)31/h2-3,5-8,10-11,22H,4,9,12-18H2,1H3,(H,27,30) |
| SMILES Code | CC(NCCCOC1=CC=C(C(N2CCC(N3C(CCC4=C3C=CC=C4)=O)CC2)=O)C=C1)=O |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
OPC-21268; OPC21268; OPC 21268
References
1) Shinoura H, Take H, Itoh S, Hirasawa A, Inoue K, Ohno Y, Hashimoto K, Tsujimoto G. Key amino acids of vasopressin V1a receptor responsible for the species difference in the affinity of OPC-21268. FEBS Lett. 2000 Jan 28;466(2-3):255-8. Erratum in: FEBS Lett 2000 Jun 2;474(2-3):257. PubMed PMID: 10682838.
2) Sugimoto I, Narimiya N, Odagiri M, Ohnishi A, Tanaka T. Protective effect of a vasopressin-1 selective antagonist, OPC-21268, against ethanol-induced damage of the rat gastric wall. Dig Dis Sci. 1999 Mar;44(3):503-9. PubMed PMID: 10080141.