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W-54011
AOB5968
CAS: 405098-33-1
Chemical Name: N-((4-Dimethylaminophenyl)methyl)-N-(4-isopropylphenyl)-7-methoxy-1,2,3,4-tetrahydronaphthalen-1-carboxamide Hydrochloride
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $24.65 | Total: $123.25 |
| 1 | 10 | $20.88 | Total: $208.80 |
| 1 | 25 | $17.69 | Total: $442.25 |
| 1 | 50 | $15.08 | Total: $754.00 |
| 1 | 100 | $13.05 | Total: $1,305.00 |
Overview
Potent and Specific C5a Receptor Antagonist
Chemical Properties
| Molecular Formula | C30H36N2O2 • HCl |
| Molecular Weight | 493.1 |
| CAS Numbers | 405098-33-1 |
| Solubility | DMF: 30 mg/mL DMSO: 30 mg/mL Ethanol: 3 mg/mL |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | N-[[4-(dimethylamino)phenyl]methyl]-1,2,3,4-tetrahydro-7-methoxy-N-[4-(1-methylethyl)phenyl]-1-naphthalenecarboxamide, monohydrochloride |
| InChl Key | UKBJWRMNGCDKNL-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C30H36N2O2.ClH/c1-21(2)23-11-16-26(17-12-23)32(20-22-9-14-25(15-10-22)31(3)4)30(33)28-8-6-7-24-13-18-27(34-5)19-29(24)28;/h9-19,21,28H,6-8,20H2,1-5H3;1H |
| SMILES Code | CN(C)C1=CC=C(CN(C(C2CCCC3=C2C=C(OC)C=C3)=O)C4=CC=C(C(C)C)C=C4)C=C1.Cl |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
References
1) Sumichika, H., Sakata, K., Sato, N., et al. Identification of a potent and orally active non-peptide C5a receptor antagonist. The Journal of Biological Chemisty 277(51), 49403-49407 (2002).
2) Kurihara, R., Yamamoka, K., Sawamukai, N., et al. C5a promotes migration, proliferation, and vessel formation in endothelial cells. Inflamm. Res. 59(8), 659-666 (2010).