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BX513 hydrochloride
AOB0780
CAS No: 193542-65-3
Chemical Name: VUF 2274; 5-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile hydrochloride
995 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $9.35 | Total: $46.75 |
| 1 | 10 | $7.92 | Total: $79.20 |
| 1 | 25 | $6.71 | Total: $167.75 |
| 1 | 50 | $5.72 | Total: $286.00 |
| 1 | 100 | $4.95 | Total: $495.00 |
Overview
Selective CCR1 receptor antagonist
Chemical Properties
| Molecular Formula | C28H30Cl2N2O |
| Molecular Weight | 481.46 |
| CAS Numbers | 193542-65-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 5-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2-diphenylpentanenitrile hydrochloride |
| InChl Key | SSZWNUGWOGONQJ-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C28H29ClN2O.ClH/c29-26-14-12-25(13-15-26)28(32)17-20-31(21-18-28)19-7-16-27(22-30,23-8-3-1-4-9-23)24-10-5-2-6-11-24;/h1-6,8-15,32H,7,16-21H2;1H |
| SMILES Code | N#CC(C1=CC=CC=C1)(C2=CC=CC=C2)CCCN3CCC(O)(C4=CC=C(Cl)C=C4)CC3.[H]Cl |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
BX-513 hydrochloride; BX-513 HCl; BX 513 HCl; BX513 HCl; BX 513 hydrochloride; BX513 hydrochloride; VUF 2274; VUF-2274; VUF2274
References
1) Di Prisco S, Merega E, Pittaluga A. Functional adaptation of presynaptic chemokine receptors in EAE mouse central nervous system. Synapse. 2014 Nov;68(11):529-35. doi: 10.1002/syn.21774. Epub 2014 Aug 19. PubMed PMID: 25092801.
2) Di Prisco S, Summa M, Chellakudam V, Rossi PI, Pittaluga A. RANTES-mediated control of excitatory amino acid release in mouse spinal cord. J Neurochem. 2012 May;121(3):428-37. doi: 10.1111/j.1471-4159.2012.07720.x. Epub 2012 Mar 21. PubMed PMID: 22385043.