Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
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- Rare Chemicals
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- Antifungal
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- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $43.35 | Total: $216.75 |
| 1 | 10 | $36.72 | Total: $367.20 |
| 1 | 25 | $31.11 | Total: $777.75 |
| 1 | 50 | $26.52 | Total: $1,326.00 |
| 1 | 100 | $22.95 | Total: $2,295.00 |
Overview
RU-302 is a pan inhibitor of TAM Receptor blocking the interface between the TAM Ig1 ectodomain and the Gas6 Lg domain. RU-302 effectively blocks the activation of Gas6-inducible AXL and suppresses lung cancer tumor growth.
Chemical Properties
| Molecular Formula | C24H24F3N3O2S |
| Molecular Weight | 475.53 |
| CAS Numbers | 1182129-77-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1noc(C)c1CSc1ccccc1C(=O)N1CCN(CC1)c1cccc(c1)C(F)(F)F |
Storage and Handling
0C Short Term, -20C Long Term
References
Kimani SG, et al. Small molecule inhibitors block Gas6-inducible TAM activation and tumorigenicity. Sci Rep. 2017 Mar 8;7 43908.