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![[Ala11,D-Leu15]-Orexin B acetate](https://img.aobious.com/img/p/4/7/5/0/2/47502-large_default.webp "[Ala11,D-Leu15]-Orexin B acetate")
![[Ala11,D-Leu15]-Orexin B acetate](https://img.aobious.com/img/p/4/7/5/0/2/47502.jpg "[Ala11,D-Leu15]-Orexin B acetate")
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $378.25 | Total: $1,891.25 |
| 1 | 10 | $320.40 | Total: $3,204.00 |
| 1 | 25 | $271.45 | Total: $6,786.25 |
| 1 | 50 | $231.40 | Total: $11,570.00 |
| 1 | 100 | $200.25 | Total: $20,025.01 |
Overview
[Ala11,D-Leu15]-Orexin B acetate is a selective agonist of orexin-2 receptor (OX2) with an EC50 of 0.13 nM, showing 400-fold selectivity over OX1 (52 nM).
Chemical Properties
| Molecular Formula | C122H210N44O37S |
| Molecular Weight | 2917.31 |
| CAS Numbers | 3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(O)=O.CSCC[C@@H](C(N)=O)NC([C@H]([C@H](O)C)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC(CNC([C@H](C)NC([C@H](C)NC([C@H](CC1=CNC=N1)NC([C@H](CC(N)=O)NC(CNC([C@H](CO)NC([C@H](C)NC([C@H](CCC(N)=O)NC([C@@H](CC(C)C)NC([C@H](CC(C)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CCC(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H]2N(C([C@H]3N(C(CNC([C@H](CO)NC([C@H](CCCNC(N)=N)N)=O)=O)=O)CCC3)=O)CCC2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Asahi S, et al. Development of an orexin-2 receptor selective agonist, [Ala[11], D-Leu[15]]orexin-B. Bioorg Med Chem Lett. 2003;13[1] 111-113.