Pralatrexate

Pralatrexate

AT6120

CAS 146464-95-1

More details

1000 Items

$33.80

$33.80 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $22.10 Total: $110.50
110 $18.72 Total: $187.20
125 $15.86 Total: $396.50
150 $13.52 Total: $676.00
1100 $11.70 Total: $1,170.00

Overview

Pralatrexate (10-Propargyl-10-deazaaminopterin) is a folate analogue inhibitor of dihydrofolate reductase (DHFR) exhibiting high affinity for reduced folate carrier-1 (RFC-1) with antineoplastic and immunosuppressive activities.

Chemical Properties

Molecular FormulaC23H23N7O5
Molecular Weight477.47
CAS Numbers146464-95-1
SolubilityDMSO
Purity98% by HPLC
SMILES CodeNc1nc(N)c2nc(CC(CC#C)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1

Storage and Handling

0C Short Term, -20C Long Term

References

Marchi E, et al. Clin Cancer Res, 2010, 16[14], 3648-3658.