Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
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- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
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- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $141.10 | Total: $705.50 |
| 1 | 10 | $119.52 | Total: $1,195.20 |
| 1 | 25 | $101.26 | Total: $2,531.50 |
| 1 | 50 | $86.32 | Total: $4,316.00 |
| 1 | 100 | $74.70 | Total: $7,470.00 |
Overview
ARB-272572 hydrochloride is a small molecule PD-L1 inhibitor with an IC50 value of 400 pM for PD-1PD-L1 HTRF.ARB-272572 hydrochloride inhibits PD-1PD-L1 cell signaling by inducing homologous interactions with PD-L1 proteins.
Chemical Properties
| Molecular Formula | C32H36N6O4.xClH |
| CAS Numbers | 2377524-19-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
Storage and Handling
0C Short Term, -20C Long Term
References
Offringa R,et al. The expanding role for small molecules in immuno-oncology. Nat Rev Drug Discov. 2022 Nov;21[11] 821-840.