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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $71.40 | Total: $357.00 |
| 1 | 10 | $60.48 | Total: $604.80 |
| 1 | 25 | $51.24 | Total: $1,281.00 |
| 1 | 50 | $43.68 | Total: $2,184.00 |
| 1 | 100 | $37.80 | Total: $3,780.00 |
Overview
AZ-23 is an inhibitor of ATP-competitive and Trk kinase ABC. For TrkA, TrkB, FGFR1, Flt3, Ret, MuSk, Lck, the IC50s values are 2 nM, 8 nM, 24 nM, 52 nM, 55 nM, 84 nM, 99 nM, respectively.
Chemical Properties
| Molecular Formula | C17H19ClFN7O |
| Molecular Weight | 391.83 |
| CAS Numbers | 915720-21-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)Oc1cc(Nc2nc(N[C@@H](C)c3ccc(F)cn3)ncc2Cl)n[nH]1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Thress K, et al. Identification and preclinical characterization of AZ-23, a novel, selective, and orally bioavailable inhibitor of the Trk kinase pathway. Mol Cancer Ther. 2009 Jul; 8[7] 1818-27.