Desmopressin acetate (16679-58-6 free base)

Desmopressin acetate (16679-58-6 free base)

AT5144

CAS 62288-83-9

More details

1000 Items

$49.40

$49.40 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $32.30 Total: $161.50
110 $27.36 Total: $273.60
125 $23.18 Total: $579.50
150 $19.76 Total: $988.00
1100 $17.10 Total: $1,710.00

Overview

Desmopressin acetate (16679-58-6 free base) (DDAVP) is the synthetic analog of the antidiuretic hormone arginine vasopressin. Vasopressin Receptor The antidiuretic properties of desmopressin have led to its use in polyuric conditions including primary nocturnal enuresis, nocturia, and diabetes insipidus. Desmopressin acetate (16679-58-6 free base) works by limiting the amount of water that is eliminated in the urine. Desmopressin acetate (16679-58-6 free base) binds to V2 receptors in renal collecting ducts, increasing water reabsorption. It also stimulates the release of von Willebrand factor from endothelial cells by acting on the V2 receptor.

Chemical Properties

Molecular FormulaC48H68N14O14S2
Molecular Weight1129.26
CAS Numbers62288-83-9
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(O)=O.NC(=O)CCC1NC(=O)C(Cc2ccccc2)NC(=O)C(Cc2ccc(O)cc2)NC(=O)CCSSCC(NC(=O)C(CC(N)=O)NC1=O)C(=O)N1CCCC1C(=O)NC(CCCNC(N)=N)C(=O)NCC(N)=O

Storage and Handling

0C Short Term, -20C Long Term

References

Kaufmann JE, et al. Desmopressin [DDAVP] induces NO production in human endothelial cells via V2 receptor- and cAMP-mediated signaling. J Thromb Haemost. 2003 Apr;1[4] 821-8.