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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $155.55 | Total: $777.75 |
| 1 | 10 | $131.76 | Total: $1,317.60 |
| 1 | 25 | $111.63 | Total: $2,790.75 |
| 1 | 50 | $95.16 | Total: $4,758.00 |
| 1 | 100 | $82.35 | Total: $8,235.00 |
Overview
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-?-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is also an inhibitor of VEGF-R2 with IC50 of 52 nM.
Chemical Properties
| Molecular Formula | C19H22O7 |
| Molecular Weight | 362.37 |
| CAS Numbers | 253863-19-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc(O)c2c(c1)C=CC[C@H](O)[C@H](O)C(=O)C=CC[C@H](C)OC2=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Dakas PY, et al. Modular synthesis of radicicol A and related resorcylic acid lactones, potent kinase inhibitors. Angew Chem Int Ed Engl. 2007;46[36] 6899-902.