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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $249.90 | Total: $1,249.50 |
| 1 | 10 | $211.68 | Total: $2,116.80 |
| 1 | 25 | $179.34 | Total: $4,483.50 |
| 1 | 50 | $152.88 | Total: $7,644.00 |
| 1 | 100 | $132.30 | Total: $13,230.01 |
Overview
HS024 is a highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks ?-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo.
Chemical Properties
| Molecular Formula | C58H79N19O10S2 |
| Molecular Weight | 1266.5 |
| CAS Numbers | 212370-59-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](CC4=CC5=C(C=C4)C=CC=C5)NC(=O)[C@H](CC6=CN=CN6)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCC)NC(=O)[C@@H](NC(C)=O)CSSC[C@@H](C(N)=O)NC(=O)CNC3=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Jonsson et al [2001] Melanocortin receptor agonist transiently increases oxygen consumption in rats. Neuroreport 12 3703 PMID