Categories
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- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $237.15 | Total: $1,185.75 |
| 1 | 10 | $200.88 | Total: $2,008.80 |
| 1 | 25 | $170.19 | Total: $4,254.75 |
| 1 | 50 | $145.08 | Total: $7,254.00 |
| 1 | 100 | $125.55 | Total: $12,555.01 |
Overview
BGB-102 (JNJ-26483327) is a kinase inhibitor targeting FLT3 and YES1 and an antagonist targeting EGFR and VEGFR3, which may be useful in the study of macular degeneration and diseases associated with genetic disorders and malformations.
Chemical Properties
| Molecular Formula | C22H25BrN4O2 |
| Molecular Weight | 457.36 |
| CAS Numbers | 807640-87-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | BrC1=CC=C2C(=C1)NC=3N=CN=C4C=C(OC)C(OCCCCCN(C)C2)=CC43 |
Storage and Handling
0C Short Term, -20C Long Term
References
Gijsen M, et al. HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer. PLoS Biol. 2010 Dec 21;8[12] e1000563.