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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $81.60 | Total: $408.00 |
| 1 | 10 | $69.12 | Total: $691.20 |
| 1 | 25 | $58.56 | Total: $1,464.00 |
| 1 | 50 | $49.92 | Total: $2,496.00 |
| 1 | 100 | $43.20 | Total: $4,320.00 |
Overview
Acrizanib (LHA510) is a VEGFR-2 inhibitor with an IC50 of 17.4 nM for BaF3-VEGFR-2.
Chemical Properties
| Molecular Formula | C20H18F3N7O2 |
| Molecular Weight | 445.4 |
| CAS Numbers | 1229453-99-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CNCc1cc(Oc2ccc3n(ccc3c2)C(=O)Nc2cc(n(C)n2)C(F)(F)F)ncn1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Adams CM, et al. The Discovery of N-[1-Methyl-5-[trifluoromethyl]-1H-pyrazol-3-yl]-5-[[6- [[methylamino]methyl]pyrimidin-4-yl]oxy]-1H-indole-1-carboxamide [Acrizanib], a VEGFR-2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration. J Med Chem. 2018 Feb 22;61[4] 1622-1635.