(Rac)-Modipafant

(Rac)-Modipafant

AT28081

CAS 122956-68-7

More details

1000 Items

$241.80

$241.80 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $158.10 Total: $790.50
110 $133.92 Total: $1,339.20
125 $113.46 Total: $2,836.50
150 $96.72 Total: $4,836.00
1100 $83.70 Total: $8,370.00

Overview

(Rac)-Modipafantis an orally available and selective platelet-activating factor receptor (PAFR) antagonist that inhibits PAF-induced aggregation of washed platelets in rabbits, and can be used to study arthritis and ischemiareperfusion (IR) in the superior mesenteric artery (SMA) of the rat.

Chemical Properties

Molecular FormulaC34H29ClN6O3
Molecular Weight605.09
CAS Numbers122956-68-7
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(OCC)C1=C(NC(=C(C(=O)NC2=NC=CC=C2)C1C=3C=CC=CC3Cl)C)C=4C=CC(=CC4)N5C(=NC=6C=NC=CC65)C

Storage and Handling

0C Short Term, -20C Long Term

References

Guerrero AT, Zarpelon AC, Vieira SM, Pinto LG, Ferreira SH, Cunha FQ, Verri WA Jr, Cunha TM. The role of PAFPAFR signaling in zymosan-induced articular inflammatory hyperalgesia. Naunyn Schmiedebergs Arch Pharmacol. 2013 Jan;386[1] 51-9. doi 10.1007s00210-012-0813-4. Erratum in Naunyn Schmiedebergs Arch Pharmacol. 2013 Apr;386[4] 351. Zaperlon, Ana C [corrected to Zarpelon, Ana C]. PubMed PMID 23187752.