Categories
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- Protein Control Ligand
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- Function Modulators
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.05 | Total: $225.25 |
| 1 | 10 | $38.16 | Total: $381.60 |
| 1 | 25 | $32.33 | Total: $808.25 |
| 1 | 50 | $27.56 | Total: $1,378.00 |
| 1 | 100 | $23.85 | Total: $2,385.00 |
Overview
EB-47 mimics the substrate NAD+ and extends from the nicotinamide to the adenosine subsite.EB-47, a potent and selective PARP-1ARTD-1 inhibitor with an IC50 value of 45 nM, shows modest potency against ARTD5 with an IC50 value of 410 nM.
Chemical Properties
| Molecular Formula | C24H27N9O6 |
| Molecular Weight | 537.53 |
| CAS Numbers | 366454-36-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](C(=O)N4CCN(CC(NC5=C6C(C(=O)NC6)=CC=C5)=O)CC4)[C@H]1O |
Storage and Handling
0C Short Term, -20C Long Term
References
Haikarainen T, et al. Evaluation and Structural Basis for the Inhibition of Tankyrases by PARP Inhibitors.ACS Med Chem Lett.