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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $68.85 | Total: $344.25 |
| 1 | 10 | $58.32 | Total: $583.20 |
| 1 | 25 | $49.41 | Total: $1,235.25 |
| 1 | 50 | $42.12 | Total: $2,106.00 |
| 1 | 100 | $36.45 | Total: $3,645.00 |
Overview
TC-MCH 7c is an oral, selectable and blood-brain barrier penetrating MCH1R antagonist with IC50 performance of 5.6 nM against hMCH1R, and TC-MCH 7c is a phenylpyridone derivative with MCH1R Ki of 3.4 nM against human. In mice, MCH1R Ki was 3.0 nM.
Chemical Properties
| Molecular Formula | C24H25FN2O3 |
| Molecular Weight | 408.47 |
| CAS Numbers | 864756-35-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Fc1ccc(COc2ccn(-c3ccc(OCCN4CCCC4)cc3)c(=O)c2)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Ito M, et al. Melanin-concentrating hormone 1-receptor antagonist suppresses body weight gain correlated with high receptor occupancy levels in diet-induced obesity mice. Eur J Pharmacol. 2009 Dec 10;624[1-3] 77-83.