Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $215.90 | Total: $1,079.50 |
| 1 | 10 | $182.88 | Total: $1,828.80 |
| 1 | 25 | $154.94 | Total: $3,873.50 |
| 1 | 50 | $132.08 | Total: $6,604.00 |
| 1 | 100 | $114.30 | Total: $11,430.01 |
Overview
TR antagonist 1 is a highly potent thyroid hormone receptor (TR) antagonist (IC50 of 36 and 22 nM for TR? and TR?, respectively) that can be used to study diseases caused by endocrine abnormalities.
Chemical Properties
| Molecular Formula | C25H23Br2NO4 |
| Molecular Weight | 561.26 |
| CAS Numbers | 500794-88-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)c1cc(Oc2c(Br)cc(CCC(O)=O)cc2Br)cc(C=Cc2ccncc2)c1O |
Storage and Handling
0C Short Term, -20C Long Term
References
Koehler K, et al. Thyroid receptor ligands. 6. A high affinity "direct antagonist" selective for the thyroid hormone receptor. J Med Chem. 2006 Nov 16;49[23] 6635-7.