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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.45 | Total: $157.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 100 | $16.65 | Total: $1,665.00 |
Overview
TAK-593 is an effective VEGFR and PDGFR family inhibitor (IC50s: 3.2, 0.95, 1.1, 4.3, and 13 nM for VEGFR1, VEGFR2, VEGFR3, PDFGR?, and PDFGR?, respectively).
Chemical Properties
| Molecular Formula | C23H23N7O3 |
| Molecular Weight | 445.47 |
| CAS Numbers | 1005780-62-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1cc(C(=O)Nc2cc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)ccc2C)n(C)n1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Miyamoto N, et al. Discovery of N-[5-[{2-[[cyclopropylcarbonyl]amino]imidazo[1,2-b]pyridazin-6-yl}oxy]-2-methylphenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide [TAK-593], a highly potent VEGFR2 kinase inhibitor. Bioorg Med Chem. 2013 Apr 15;21[8] 2333-2345.