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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $27.20 | Total: $136.00 |
| 1 | 10 | $23.04 | Total: $230.40 |
| 1 | 25 | $19.52 | Total: $488.00 |
| 1 | 50 | $16.64 | Total: $832.00 |
| 1 | 100 | $14.40 | Total: $1,440.00 |
Overview
AAL-993 is a potent VEGFR inhibitor with IC50s of 130 nM, 23 nM and 18 nM for VEGFR1, VEGFR2 and VEGFR3, respectively. AAL993 has a weak inhibitory effect on other tyrosine kinases. AAL993 also shows potent antiangiogenic and antitumor activities.
Chemical Properties
| Molecular Formula | C20H16F3N3O |
| Molecular Weight | 371.36 |
| CAS Numbers | 269390-77-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | FC(F)(F)c1cccc(NC(=O)c2ccccc2NCc2ccncc2)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Hyun Seung Ban, et al. Suppression of hypoxia-induced HIF-1alpha accumulation by VEGFR inhibitors Different profiles of AAL993 versus SU5416 and KRN633. Cancer Lett. 2010 Oct 1;296[1] 17-26.