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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $43.35 | Total: $216.75 |
| 1 | 10 | $36.72 | Total: $367.20 |
| 1 | 25 | $31.11 | Total: $777.75 |
| 1 | 50 | $26.52 | Total: $1,326.00 |
| 1 | 100 | $22.95 | Total: $2,295.00 |
Overview
YNT-185 is a nonpeptide, selective agonist of the orexin type-2 receptor (OX2R), with EC50 values of 0.028 ?M for OX2R and 2.75 ?M for OX1R. Additionally, YNT-185 effectively alleviates symptoms of narcolepsy-cataplexy in mouse models.
Chemical Properties
| Molecular Formula | C33H37N5O5S |
| Molecular Weight | 615.74 |
| CAS Numbers | 1804978-81-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | S(NC1=CC(NCCNC(=O)C2=C(N(C)C)C=CC=C2)=CC=C1)(=O)(=O)C3=C(OC)C=CC(=C3)C4=CC(C(N(C)C)=O)=CC=C4 |
Storage and Handling
0C Short Term, -20C Long Term
References
Irukayama-Tomobe Y, et al. Nonpeptide orexin type-2 receptor agonist ameliorates narcolepsy-cataplexy symptoms in mouse models. Proc Natl Acad Sci U S A. 2017;114[22] 5731-5736.