Categories
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- Protein Control Ligand
- Pathway Inhibitors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $36.55 | Total: $182.75 |
| 1 | 10 | $30.96 | Total: $309.60 |
| 1 | 25 | $26.23 | Total: $655.75 |
| 1 | 50 | $22.36 | Total: $1,118.00 |
| 1 | 100 | $19.35 | Total: $1,935.00 |
Overview
CZC-25146 is a selective LRRK2 inhibitor with IC50 of 4.76 nM6.87 nM for wild type LRRK2 and G2019S LRRK2, respectively.
Chemical Properties
| Molecular Formula | C22H26ClFN6O4S |
| Molecular Weight | 525 |
| CAS Numbers | 1330003-04-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.COc1cc(ccc1Nc1ncc(F)c(Nc2ccccc2NS(C)(=O)=O)n1)N1CCOCC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Ramsden N, et al. Chemoproteomics-based design of potent LRRK2-selective lead compounds that attenuate Parkinson's disease-related toxicity in human neurons. ACS Chem Biol. 2011 Oct 21;6[10] 1021-8.