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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $62.90 | Total: $314.50 |
| 1 | 10 | $53.28 | Total: $532.80 |
| 1 | 25 | $45.14 | Total: $1,128.50 |
| 1 | 50 | $38.48 | Total: $1,924.00 |
| 1 | 100 | $33.30 | Total: $3,330.00 |
Overview
RBN-3143 is a potent inhibitor of NAD+-competitive catalytic PARP14 (IC50= 4 nM), which inhibits ADP-ribosylation mediated by PARP14 and stabilizes PARP14 in cell lines, demonstrating research potential for lung inflammation.
Chemical Properties
| Molecular Formula | C22H28FN3O4S |
| Molecular Weight | 449.54 |
| CAS Numbers | 2360853-16-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(=O)N1CCC(COc2cc(F)c3c(c2)nc(CSC2CCOCC2)[nH]c3=O)CC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Niepel M, et, al. The PARP14 inhibitor RBN-3143 suppresses lung inflammation in preclinical models. European Respiratory Journal 2022 60 4642.