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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $67.15 | Total: $335.75 |
| 1 | 10 | $56.88 | Total: $568.80 |
| 1 | 25 | $48.19 | Total: $1,204.75 |
| 1 | 50 | $41.08 | Total: $2,054.00 |
| 1 | 100 | $35.55 | Total: $3,555.00 |
Overview
BMS-1001 is a potent inhibitor of PD-1PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved fluorescence binding assay).
Chemical Properties
| Molecular Formula | C35H34N2O7 |
| Molecular Weight | 594.7 |
| CAS Numbers | 2113650-03-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC1=CC(CN[C@H](CO)C(O)=O)=C(OCC2=CC(=CC=C2)C#N)C=C1OCC1=C(C)C(=CC=C1)C1=CC2=C(OCCO2)C=C1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Skalniak L , Zak K M , Guzik K , et al. Small-molecule inhibitors of PD-1PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells[J]. Oncotarget, 2017, 8[42].