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Overview
Betamethasone Dipropionate is the 17, 21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate (SCH 11460) binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.
Chemical Properties
| Molecular Formula | C28H37FO7 |
| Molecular Weight | 504.59 |
| CAS Numbers | 5593-20-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(COC(CC)=O)(=O)[C@]1(OC(CC)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H] |
Storage and Handling
0C Short Term, -20C Long Term
References
Park JM, et al. J Am Acad Dermatol. 2013 Sep;69[3] 492-3.