Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Epigenetics
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- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
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- Rare Chemicals
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- Antifungal
- Antioxidant
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- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $69.70 | Total: $348.50 |
| 1 | 10 | $59.04 | Total: $590.40 |
| 1 | 25 | $50.02 | Total: $1,250.50 |
| 1 | 50 | $42.64 | Total: $2,132.00 |
| 1 | 100 | $36.90 | Total: $3,690.00 |
Overview
BLU-945 is a potent, highly selective, reversible, and orally active epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor effective against EGFR with L858R, exon 19 deletion, T790M, and C797S mutations. It is used in lung cancer research, including non-small cell lung cancer (NSCLC).
Chemical Properties
| Molecular Formula | C28H37FN6O3S |
| Molecular Weight | 556.7 |
| CAS Numbers | 2660250-10-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CO[C@@H]1CCN(C[C@@H]1F)c1nccc(Nc2cc3c(ccc(N4C[C@H](CS(C)(=O)=O)[C@H]4C)c3cn2)C(C)C)n1 |
Storage and Handling
0C Short Term, -20C Long Term
References
John Emmerson Campbell, et al. Inhibitors of mutant forms of egfr. Patent WO2021133809A1.