Categories
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- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
Sunvozertinib (DZD9008) is a potent ErbBs and BTK inhibitor with inhibitory effects on EGFR, Her2, and mutant epidermal growth factor. It inhibits EGFR exon 20 NPH insertion, EGFR exon 20 ASV insertion, EGFR L858R and T790M mutation, and Her2 exon 20 YVMA and EGFR WT A431, with IC50 values of 20.4, 20.4, 1.1, 7.5, and 80.4 nM, respectively.
Chemical Properties
| Molecular Formula | C29H35ClFN7O3 |
| Molecular Weight | 584.08 |
| CAS Numbers | 2370013-12-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc(N2CC[C@H](C2)N(C)C)c(NC(=O)C=C)cc1Nc1nccc(Nc2cc(Cl)c(F)cc2C(C)(C)O)n1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Zhengtao LI, et al. Erbbbtk inhibitors. WO2019149164A1.