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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $143.65 | Total: $718.25 |
| 1 | 10 | $121.68 | Total: $1,216.80 |
| 1 | 25 | $103.09 | Total: $2,577.25 |
| 1 | 50 | $87.88 | Total: $4,394.00 |
| 1 | 100 | $76.05 | Total: $7,605.00 |
Overview
Simotinib (AL-6802) is a selective and orally bioactive EGFR tyrosine kinase inhibitor (IC50: 19.9 nM) with anti-tumour activity for the study of non-small cell lung cancer.
Chemical Properties
| Molecular Formula | C25H26ClFN4O4 |
| Molecular Weight | 500.95 |
| CAS Numbers | 944258-89-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCN1CC2(CC2)C2(C1)OCCO2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Hu XS, et al. Safety, tolerability, and pharmacokinetics of simotinib, a novel specific EGFR tyrosine kinase inhibitor, in patients with advanced non-small cell lung cancer results of a phase Ib trial. Cancer Manag Res. 2019;11 4449-4459. Published 2019.