Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Cytokine Receptors
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- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
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- Rare Chemicals
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- Antioxidant
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- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $253.30 | Total: $1,266.50 |
| 1 | 10 | $214.56 | Total: $2,145.60 |
| 1 | 25 | $181.78 | Total: $4,544.50 |
| 1 | 50 | $154.96 | Total: $7,748.00 |
| 1 | 100 | $134.10 | Total: $13,410.01 |
Overview
EMD57033 is a cardiac troponin C (cTnC) activator, a dominant Ca2+ sensitizer, which functions by binding to cardiacslow skeletal troponin C heterodimers to promote cardiac contraction.
Chemical Properties
| Molecular Formula | C22H23N3O4S |
| Molecular Weight | 425.5 |
| CAS Numbers | 147527-31-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(C1=CC(OC)=C(C=C1)OC)N2C3=CC=C(C([C@H](S4)C)=NNC4=O)C=C3CCC2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Papadaki M, et al. Uncoupling of myofilament Ca2+ sensitivity from troponin I phosphorylation by mutations can be reversed by epigallocatechin-3-gallate. Cardiovasc Res. 2015 ; 108[1] 99-110.