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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $36.55 | Total: $182.75 |
| 1 | 10 | $30.96 | Total: $309.60 |
| 1 | 25 | $26.23 | Total: $655.75 |
| 1 | 50 | $22.36 | Total: $1,118.00 |
| 1 | 100 | $19.35 | Total: $1,935.00 |
Overview
HIF-2? agonist 2 is an HIF-2? agonist with an EC50 value of 1.68 ?M for HIF-2?. HIF-2? agonist 2 can promote the stability of the ARNT AB ring in the 3z structure of HIF-2a-ARNT complex without cytotoxicity to 786-o-Reha-Luc cells. HIF-2? agonist 2 can be used in the study of oxygen metabolism and is closely related to the occurrence of cancer.
Chemical Properties
| Molecular Formula | C13H8Br2N2O2S |
| Molecular Weight | 416.09 |
| CAS Numbers | 2750141-15-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C=1C=2C(S(=O)(=O)N1)=CC=CC2)C3=CC(Br)=CC(Br)=C3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Yu Y, et al. Insight into the binding mode of HIF-2 agonists through molecular dynamic simulations and biological validation. Eur J Med Chem. 2021;211 112999.