Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $44.20 | Total: $221.00 |
| 1 | 10 | $37.44 | Total: $374.40 |
| 1 | 25 | $31.72 | Total: $793.00 |
| 1 | 50 | $27.04 | Total: $1,352.00 |
| 1 | 100 | $23.40 | Total: $2,340.00 |
Overview
PT-2385 is a selective inhibitor of HIF-2? with a dissociation constant (Kd) of less than 50 nM (Kd<50 nM).
Chemical Properties
| Molecular Formula | C17H12F3NO4S |
| Molecular Weight | 383.34 |
| CAS Numbers | 1672665-49-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CS(=O)(=O)c1ccc(Oc2cc(F)cc(c2)C#N)c2CC(F)(F)[C@@H](O)c12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Eli Wallace, Ph.D. PT2385 HIF-2? Antagonist for the Treatment of VHL Mutant ccRCC. 12th International VHL Medical Symposium April 8, 2016.