Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Customized Screening Library
- Ultra Pure Pharmacological Standard
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- Proteins and Antibodies
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $577.15 | Total: $2,885.75 |
| 1 | 10 | $488.88 | Total: $4,888.80 |
| 1 | 25 | $414.19 | Total: $10,354.76 |
| 1 | 50 | $353.08 | Total: $17,654.00 |
| 1 | 100 | $305.55 | Total: $30,555.01 |
Overview
IL-17A inhibitor 1 is a IL-17A inhibitor with IC50 of <9.45 nM in alphalisa assay. IL-17A inhibitor 1 inhibits HT-29 cells with IC50 of 9.3 nM.
Chemical Properties
| Molecular Formula | C24H27F5N8O4 |
| Molecular Weight | 586.51 |
| CAS Numbers | 2452464-73-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COC[C@@H](N1C[C@H](NC1=O)C(F)(F)F)c1cnn2cc(nc2c1)[C@@H](NC(=O)c1nonc1C)C1CCC(F)(F)CC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
COATES DAVID ANDREW, et al. IMIDAZO[1,2-B]PYRIDAZINE IL-17A INHIBITORS. Patent WO2020146194.