Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Molecular Probes
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- Alzheimer's Disease
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- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
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- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $141.10 | Total: $705.50 |
| 1 | 10 | $119.52 | Total: $1,195.20 |
| 1 | 25 | $101.26 | Total: $2,531.50 |
| 1 | 50 | $86.32 | Total: $4,316.00 |
| 1 | 100 | $74.70 | Total: $7,470.00 |
Overview
PF-07038124 HCl is a selective and potent PDE4 inhibitor with an IC50 of 0.5 nM for PDE4B2.PF-07038124 HCl inhibits IL-13, IL-4, and IFN?, and can be used in the study of skin disorders such as atopic dermatitis and plaque psoriasis.
Chemical Properties
| Molecular Formula | C18H23BClNO4 |
| Molecular Weight | 363.64 |
| CAS Numbers | 2415317-57-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(CCC)C=1C=C(C=CC1OC)C=2C=C(C=NC2)[C@H]3CB(O)OC3.Cl |
Storage and Handling
0C Short Term, -20C Long Term
References
Blauvelt A,et al. Next Generation PDE4 Inhibitors that Selectively Target PDE4BD Subtypes A Narrative Review. Dermatol Ther [Heidelb]. 2023 Dec;13[12] 3031-3042.