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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.90 | Total: $144.50 |
| 1 | 10 | $24.48 | Total: $244.80 |
| 1 | 25 | $20.74 | Total: $518.50 |
| 1 | 50 | $17.68 | Total: $884.00 |
| 1 | 100 | $15.30 | Total: $1,530.00 |
Overview
CP 424174 is an inhibitor of IL-1? post-translational processing with IC50 of 210 nM. Inhibits the formation of mature IL-1?. Indirectly inhibits NLRP3. Active in vivo and orally bioavailable.
Chemical Properties
| Molecular Formula | C22H29ClN2O4S |
| Molecular Weight | 452.99 |
| CAS Numbers | 210825-31-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)c1cc(Cl)cc(C(C)C)c1NC(=O)NS(=O)(=O)c1cccc(c1)C(C)(C)O |
Storage and Handling
0C Short Term, -20C Long Term
References
Perregaux D G , Mcniff P , Laliberte R , et al. Identification and characterization of a novel class of interleukin-1 post-translational processing inhibitors.[J]. Journal of Pharmacology & Experimental Therapeutics, 2001, 299[1] 187.