Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $58.65 | Total: $293.25 |
| 1 | 10 | $49.68 | Total: $496.80 |
| 1 | 25 | $42.09 | Total: $1,052.25 |
| 1 | 50 | $35.88 | Total: $1,794.00 |
| 1 | 100 | $31.05 | Total: $3,105.00 |
Overview
TR-14035 (MDK-1191) is a dual antagonist of ?4?7?4?1 integrins (IC50s: 787nM).
Chemical Properties
| Molecular Formula | C24H21Cl2NO5 |
| Molecular Weight | 474.33 |
| CAS Numbers | 232271-19-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cccc(OC)c1-c1ccc(C[C@H](NC(=O)c2c(Cl)cccc2Cl)C(O)=O)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Sircar I, et al. Synthesis and SAR of N-benzoyl-L-biphenylalanine derivatives discovery of TR-14035, a dual alpha[4]beta[7]alpha[4]beta[1] integrin antagonist. Bioorg Med Chem. 2002 Jun;10[6] 2051-66.