Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
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- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $30.60 | Total: $153.00 |
| 1 | 10 | $25.92 | Total: $259.20 |
| 1 | 25 | $21.96 | Total: $549.00 |
| 1 | 50 | $18.72 | Total: $936.00 |
| 1 | 100 | $16.20 | Total: $1,620.00 |
Overview
Branaplam (LMI 070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator.
Chemical Properties
| Molecular Formula | C22H27N5O2 |
| Molecular Weight | 393.48 |
| CAS Numbers | 1562338-42-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC1(C)CC(CC(C)(C)N1)Oc1ccc(nn1)-c1ccc(cc1O)-c1cn[nH]c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Palacino J, et al. SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice. Nat Chem Biol. 2015 Jul;11[7] 511-517.