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PD-98059
AOB2598
CAS No:167869-21-8
Chemical Name: PD98059; 2-(2-Amino-3-methoxyphenyl)-4H-1-benzopyran-4-one
499 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $9.35 | Total: $46.75 |
| 1 | 10 | $7.92 | Total: $79.20 |
| 1 | 25 | $6.71 | Total: $167.75 |
| 1 | 50 | $5.72 | Total: $286.00 |
| 1 | 100 | $4.95 | Total: $495.00 |
Overview
Selective inhibitor of MEK and blocker of MAPK
Chemical Properties
| Molecular Formula | C16H13NO3 |
| Molecular Weight | 257.3 |
| CAS Numbers | 167869-21-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 2-(2-amino-3-methoxyphenyl)-4H-chromen-4-one |
| InChl Key | QFWCYNPOPKQOKV-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C16H13NO3/c1-19-14-8-4-6-11(16(14)17)15-9-12(18)10-5-2-3-7-13(10)20-15/h2-9H,17H2,1H3 |
| SMILES Code | O=C1C=C(C2=CC=CC(OC)=C2N)OC3=C1C=CC=C3 |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
PD98059; PD-98059; PD 98059; PD098059
References
1) Huang CT, Huang DY, Hu CJ, Wu D, Lin WW. Energy adaptive response during parthanatos is enhanced by PD98059 and involves mitochondrial function but not autophagy induction. Biochim Biophys Acta. 2014 Mar;1843(3):531-43. PubMed PMID: 24321770.
2) Lee JM, Kim JD, Oh EJ, Oh SH, Lee JH, Im GI. PD98059-impregnated functional PLGA Scaffold for direct tissue engineering promotes chondrogenesis and prevents hypertrophy from mesenchymal stem cells. Tissue Eng Part A. 2014 Mar;20(5-6):982-91. doi: 10.1089/ten.TEA.2013.0290. Epub 2013 Dec 11. PubMed PMID: 24188591; PubMed Central PMCID: PMC3938927.
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