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NSC803790 (PD-1 Inhibitor 16)
AOB13070
CAS: 2005454-12-4
Chemical Name: NSC803790; Aurigene Compound 16; (2S)-2-[[(1S)-3-Amino-3-oxo-1-(3-piperazin-1-yl-1,2,4-oxadiazol-5-yl)propyl]carbamoylamino]-3-hydroxybutanoic acid
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $58.65 | Total: $293.25 |
| 1 | 10 | $49.68 | Total: $496.80 |
| 1 | 25 | $42.09 | Total: $1,052.25 |
| 1 | 50 | $35.88 | Total: $1,794.00 |
| 1 | 100 | $31.05 | Total: $3,105.00 |
Overview
Novel inhibitor of PD-I/PD-L1 interaction to be used as a negative immune checkpoint regulatory and antineoplastic agent
Chemical Properties
| Molecular Formula | C14H23N7O6 |
| Molecular Weight | 385.38 |
| CAS Numbers | 2005454-12-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | (2S)-2-[[(1S)-3-Amino-3-oxo-1-(3-piperazin-1-yl-1,2,4-oxadiazol-5-yl)propyl]carbamoylamino]-3-hydroxybutanoic acid |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
Synonyms
AURIGENE COMPOUND 16; NSC803790; NSC-803790; NSC 803790
References
1) Pottayil Govindan Nair Sasikumar , et al. 3-substituted-1,2,4-oxadiazole and thiadiazole compounds as immunomodulators. WO2016142886A2.