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Overview
Dehydroabiethylamine (NSC-2955) is an inducer of hepatic CYP2B activity. Dehydroabiethylamine inhibits pyruvate dehydrogenase kinases (PDKs) and intracellular cholesterol transport with anti-tumor activity.
Chemical Properties
| Molecular Formula | C20H31N |
| Molecular Weight | 285.47 |
| CAS Numbers | 1446-61-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H][C@@]12CCc3cc(ccc3[C@@]1(C)CCC[C@@]2(C)CN)C(C)C |
Storage and Handling
0C Short Term, -20C Long Term
References
Kuzu OF, et al. Effect of lysosomotropic molecules on cellular homeostasis. Pharmacol Res. 2017 Mar;117 177-184.