Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
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- TNF Receptors
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Overview
NU6027 is a potent ATRCDK inhibitor, inhibits CDK12, ATR and DNA-PK with Ki of 2.5 ?M1.3 ?M, 0.4 ?M and 2.2 ?M, enter cells more readily than the 6-aminopurine-based inhibitors.
Chemical Properties
| Molecular Formula | C11H17N5O2 |
| Molecular Weight | 251.29 |
| CAS Numbers | 220036-08-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Nc1nc(N)c(N=O)c(OCC2CCCCC2)n1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Arris CE, et al. J Med Chem, 2000, 43[15], 2797-2804.