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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $45.90 | Total: $229.50 |
| 1 | 10 | $38.88 | Total: $388.80 |
| 1 | 25 | $32.94 | Total: $823.50 |
| 1 | 50 | $28.08 | Total: $1,404.00 |
| 1 | 100 | $24.30 | Total: $2,430.00 |
Overview
BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705, a GSK3? inhibitor with an IC50 of 66 nM and a Kd of 4.8 ?M, used in acute myeloid leukemia [AML] studies.
Chemical Properties
| Molecular Formula | C20H23N3O |
| Molecular Weight | 321.42 |
| CAS Numbers | 2056261-42-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC[C@]1(C2=CNNC2=NC2=C1C(=O)CC(C)(C)C2)c1ccccc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Wagner FF, et al. Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med. 2018 Mar 7;10[431].