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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $48.45 | Total: $242.25 |
| 1 | 10 | $41.04 | Total: $410.40 |
| 1 | 25 | $34.77 | Total: $869.25 |
| 1 | 50 | $29.64 | Total: $1,482.00 |
| 1 | 100 | $25.65 | Total: $2,565.00 |
Overview
AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) is a potent and selective Dyrk1B kinase inhibitor with an IC50 of 7 nM.
Chemical Properties
| Molecular Formula | C19H16N4 |
| Molecular Weight | 300.36 |
| CAS Numbers | 1679330-37-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1nccc(n1)-c1cn(Cc2ccccc2)c2cnccc12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Kettle JG, et al. Discovery and optimization of a novel series of Dyrk1B kinase inhibitors to explore a MEK resistance hypothesis. J Med Chem. 2015 Mar 26;58[6] 2834-44.