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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $393.55 | Total: $1,967.75 |
| 1 | 10 | $333.36 | Total: $3,333.60 |
| 1 | 25 | $282.43 | Total: $7,060.75 |
| 1 | 50 | $240.76 | Total: $12,038.00 |
| 1 | 100 | $208.35 | Total: $20,835.01 |
Overview
Aplaviroc (AK 602), an SDP derivative, is a CCR5 antagonist with IC50 values of 0.1-0.4 nM for HIV-1Ba-L, HIV-1JRFL, and HIV-1MOKW.
Chemical Properties
| Molecular Formula | C33H43N3O6 |
| Molecular Weight | 577.71 |
| CAS Numbers | 461443-59-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(CCC)N1C2(C(=O)N[C@]([C@H](O)C3CCCCC3)(C1=O)[H])CCN(CC4=CC=C(OC5=CC=C(C(O)=O)C=C5)C=C4)CC2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Maeda K, et al. Spirodiketopiperazine-based CCR5 inhibitor which preserves CC-chemokineCCR5 interactions and exerts potent activity against R5 human immunodeficiency virus type 1 in vitro. J Virol. 2004 Aug;78[16] 8654-62.